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1.
MDE Manage Decis Econ ; 2022 Mar 27.
Article in English | MEDLINE | ID: covidwho-2119031

ABSTRACT

We investigate the effects of lending relationships between banks and borrowers on loan supply during the economic shock caused by the coronavirus (COVID-19) pandemic. Using bank-firm matched data for Japan to control for several firm- and bank-specific unobserved effects, we show that banks with close relationships with borrowing firms offer more bank loans to these firms during the COVID-19 shock. This effect is larger if the borrowing firms' cash flows decrease substantially during the shock. These results imply that banks acted as liquidity providers for borrowers during sudden and unpredictable shocks if their relationships with firms were close.

2.
CEN Case Rep ; 11(3): 358-362, 2022 08.
Article in English | MEDLINE | ID: covidwho-1650017

ABSTRACT

As mRNA COVID-19 vaccines have become widely available, cases of new-onset glomerular disease after receiving COVID-19 vaccination have been reported. Here, we present a case of kidney biopsy-proven new-onset IgA vasculitis after receiving the mRNA-1273 (Moderna) COVID-19 vaccination. A 47-year-old man with a 10-year medical history of hypertension and hyperuricemia visited our hospital 19 days after receiving an initial mRNA-1273 COVID-19 vaccine injection for purpuric eruption on the legs and dorsal regions of the feet. Although the eruptions spontaneously improved within 5 days, they developed again at 15 days after the second injection. A histopathological examination of skin biopsy specimens was reminiscent of leukocytoclastic vasculitis, though direct immunofluorescence did not indicate IgA deposition within small vessel walls. Urinalysis indicated severe proteinuria (3 +) and occult blood (3 +). Thus, a kidney biopsy was performed and light microscopy revealed mild mesangial expansion, hypercellularity, and endocapillary hypercellularity, with cellular and fibrocellular crescents observed in three and one, respectively, of a total of 15 glomeruli. Immunofluorescence also showed diffuse granular mesangial staining (3 +) for IgA. Histopathological features were consistent with IgA vasculitis. Intravenous methylprednisolone at 1000 mg for 3 days was initiated, followed by oral prednisolone (0.6 mg/kg/day). Over the following 2-week period, serum creatinine level improved from 1.24 to 1.06 mg/dL and proteinuria decreased from 2.98 to 0.36 g/g Cr, though occult blood persisted. Findings in the present case indicate that new-onset IgA vasculitis after receiving mRNA-1273 COVID-19 vaccine can be treated with corticosteroid therapy.


Subject(s)
2019-nCoV Vaccine mRNA-1273 , COVID-19 , Glomerulonephritis, IGA , IgA Vasculitis , 2019-nCoV Vaccine mRNA-1273/adverse effects , Biopsy , COVID-19/diagnosis , Glomerular Mesangium/pathology , Glomerulonephritis, IGA/chemically induced , Glomerulonephritis, IGA/diagnosis , Humans , IgA Vasculitis/chemically induced , IgA Vasculitis/diagnosis , Immunoglobulin A , Male , Methylprednisolone/therapeutic use , Middle Aged , Proteinuria/etiology
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